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RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration
Modulation of integrin activation is important in many cellular functions including adhesion, migration, and assembly of the extracellular matrix. RSK2 functions downstream of Ras/Raf and promotes tumor cell motility and metastasis. We therefore investigated whether RSK2 affects integrin function. W...
Autores principales: | Gawecka, Joanna E., Young-Robbins, Shirley S., Sulzmaier, Florian J., Caliva, Maisel J., Heikkilä, Minna M., Matter, Michelle L., Ramos, Joe W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527930/ https://www.ncbi.nlm.nih.gov/pubmed/23118220 http://dx.doi.org/10.1074/jbc.M112.423046 |
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