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Development of a High-Performance Liquid Chromatographic Method for Determination of Letrozole in Wistar Rat Serum and its Application in Pharmacokinetic Studies

A fast, sensitive, and specific reversed-phase high-performance liquid chromatographic (RP–HPLC) method for the determination of letrozole in Wistar rat serum was developed. In this method, liquid–liquid extraction of letrozole was achieved using diethyl ether as the extracting solvent. The analysis...

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Detalles Bibliográficos
Autores principales: Acharjya, Sasmita Kumari, Bhattamisra, Subrat Kumar, Muddana, Bhanoji Rao E., Bera, Ravikumar V. V., Panda, Pinakini, Panda, Bibhu Prasad, Mishra, Gitanjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528055/
https://www.ncbi.nlm.nih.gov/pubmed/23264941
http://dx.doi.org/10.3797/scipharm.1206-06