An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2

[Image: see text] Telomeric repeat-containing RNA (TERRA) is important for telomere regulation, but the structural basis for how TERRA localizes to chromosome ends is unknown. Here we report on studies exploring whether the TERRA G-quadruplex structure is critical for binding to telomeres. We demons...

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Detalles Bibliográficos
Autores principales: Biffi, Giulia, Tannahill, David, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528108/
https://www.ncbi.nlm.nih.gov/pubmed/22780456
http://dx.doi.org/10.1021/ja305734x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528108/
https://www.ncbi.nlm.nih.gov/pubmed/22780456
http://dx.doi.org/10.1021/ja305734x

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