Nodularin Exposure Induces SOD1 Phosphorylation and Disrupts SOD1 Co-localization with Actin Filaments

Apoptotic cell death is induced in primary hepatocytes by the Ser/Thr protein phosphatase inhibiting cyanobacterial toxin nodularin after only minutes of exposure. Nodularin-induced apoptosis involves a rapid development of reactive oxygen species (ROS), which can be delayed by the Ca(2+)/calmodulin...

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Detalles Bibliográficos
Autores principales: Hjørnevik, Linda V., Fismen, Lise, Young, Fiona M., Solstad, Therese, Fladmark, Kari E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528258/
https://www.ncbi.nlm.nih.gov/pubmed/23242317
http://dx.doi.org/10.3390/toxins4121482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528258/
https://www.ncbi.nlm.nih.gov/pubmed/23242317
http://dx.doi.org/10.3390/toxins4121482

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