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Nodularin Exposure Induces SOD1 Phosphorylation and Disrupts SOD1 Co-localization with Actin Filaments
Apoptotic cell death is induced in primary hepatocytes by the Ser/Thr protein phosphatase inhibiting cyanobacterial toxin nodularin after only minutes of exposure. Nodularin-induced apoptosis involves a rapid development of reactive oxygen species (ROS), which can be delayed by the Ca(2+)/calmodulin...
Autores principales: | Hjørnevik, Linda V., Fismen, Lise, Young, Fiona M., Solstad, Therese, Fladmark, Kari E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528258/ https://www.ncbi.nlm.nih.gov/pubmed/23242317 http://dx.doi.org/10.3390/toxins4121482 |
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