Binding of Hanatoxin to the Voltage Sensor of Kv2.1

Hanatoxin 1 (HaTx1) is a polypeptide toxin isolated from spider venoms. HaTx1 inhibits the voltage-gated potassium channel kv2.1 potently with nanomolar affinities. Its receptor site has been shown to contain the S3b-S4a paddle of the voltage sensor (VS). Here, the binding of HaTx1 to the VSs of hum...

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Detalles Bibliográficos
Autores principales: Chen, Rong, Robinson, Anna, Chung, Shin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528262/
https://www.ncbi.nlm.nih.gov/pubmed/23250329
http://dx.doi.org/10.3390/toxins4121552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528262/
https://www.ncbi.nlm.nih.gov/pubmed/23250329
http://dx.doi.org/10.3390/toxins4121552

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