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Diversity in Glycosaminoglycan Binding Amongst hMPV G Protein Lineages

We have previously shown that hMPV G protein (B2 lineage) interacts with cellular glycosaminoglycans (GAGs). In this study we examined subtypes A1, A2 and B1 for this interaction. GAG-dependent infectivity of available hMPV strains was demonstrated using GAG-deficient cells and heparin competition....

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Detalles Bibliográficos
Autores principales: Adamson, Penelope, Thammawat, Sutthiwan, Muchondo, Gamaliel, Sadlon, Tania, Gordon, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528290/
https://www.ncbi.nlm.nih.gov/pubmed/23242371
http://dx.doi.org/10.3390/v4123785