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Assessment of Integration-defective HIV-1 and EIAV Vectors In Vitro and In Vivo

The interest in integrase-defective lentiviral vectors (IDLVs) stems from their potential advantage of large cloning capacity and broad cell tropism while avoiding the possibility of insertional mutagenesis. Here, we directly compared the transducing potential of IDLVs based on the equine infectious...

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Detalles Bibliográficos
Autores principales: Ellis, Scott, Fong-Wong, Liang, Iqball, Sharifah, Thoree, Vinay, Mitrophanous, Kyriacos A, Binley, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528299/
https://www.ncbi.nlm.nih.gov/pubmed/23232328
http://dx.doi.org/10.1038/mtna.2012.53