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Enhancement of thioredoxin/glutaredoxin-mediated L-cysteine synthesis from S-sulfocysteine increases L-cysteine production in Escherichia coli

BACKGROUND: Escherichia coli has two L-cysteine biosynthetic pathways; one is synthesized from O-acetyl L-serine (OAS) and sulfate by L-cysteine synthase (CysK), and another is produced via S-sulfocysteine (SSC) from OAS and thiosulfate by SSC synthase (CysM). SSC is converted into L-cysteine and su...

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Detalles Bibliográficos
Autores principales: Nakatani, Takeshi, Ohtsu, Iwao, Nonaka, Gen, Wiriyathanawudhiwong, Natthawut, Morigasaki, Susumu, Takagi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528435/
https://www.ncbi.nlm.nih.gov/pubmed/22607201
http://dx.doi.org/10.1186/1475-2859-11-62