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A novel model-based approach for dose determination of glycopyrronium bromide in COPD
BACKGROUND: Glycopyrronium bromide (NVA237) is an inhaled long-acting muscarinic antagonist in development for treatment of COPD. This study compared the efficacy and safety of once-daily (OD) and twice-daily (BID) glycopyrronium bromide regimens, using a novel model-based approach, in patients with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528484/ https://www.ncbi.nlm.nih.gov/pubmed/23217058 http://dx.doi.org/10.1186/1471-2466-12-74 |