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δEF1 Down-Regulates ER-α Expression and Confers Tamoxifen Resistance in Breast Cancer

Resistance to tamoxifen therapy represents a major barrier to the successful treatment of breast cancer, where a loss of or reduced ER-α level is considered a primary mechanism. Understanding how ER-α expression is regulated would provide insights into new intervention points to overcome tamoxifen r...

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Detalles Bibliográficos
Autores principales: Guo, Shaocong, Li, Yaqing, Tong, Qi, Gu, Feng, Zhu, Tianhui, Fu, Li, Yang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528679/
https://www.ncbi.nlm.nih.gov/pubmed/23285017
http://dx.doi.org/10.1371/journal.pone.0052380