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δEF1 Down-Regulates ER-α Expression and Confers Tamoxifen Resistance in Breast Cancer
Resistance to tamoxifen therapy represents a major barrier to the successful treatment of breast cancer, where a loss of or reduced ER-α level is considered a primary mechanism. Understanding how ER-α expression is regulated would provide insights into new intervention points to overcome tamoxifen r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528679/ https://www.ncbi.nlm.nih.gov/pubmed/23285017 http://dx.doi.org/10.1371/journal.pone.0052380 |