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Genetic Polymorphisms of the Main Transcription Factors for Adiponectin Gene Promoter in Regulation of Adiponectin Levels: Association Analysis in Three European Cohorts

Adiponectin serum concentrations are an important biomarker in cardiovascular epidemiology with heritability etimates of 30–70%. However, known genetic variants in the adiponectin gene locus (ADIPOQ) account for only 2%–8% of its variance. As transcription factors are thought to play an under-acknow...

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Detalles Bibliográficos
Autores principales: Kedenko, Lyudmyla, Lamina, Claudia, Kiesslich, Tobias, Kapur, Karen, Bergmann, Sven, Waterworth, Dawn, Heid, Iris M., Wichmann, H.-Erich, Kedenko, Igor, Kronenberg, Florian, Paulweber, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528683/
https://www.ncbi.nlm.nih.gov/pubmed/23285067
http://dx.doi.org/10.1371/journal.pone.0052497