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Selection and Characterization of a Candidate Therapeutic Bacteriophage That Lyses the Escherichia coli O104:H4 Strain from the 2011 Outbreak in Germany

In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak st...

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Detalles Bibliográficos
Autores principales: Merabishvili, Maia, De Vos, Daniel, Verbeken, Gilbert, Kropinski, Andrew M., Vandenheuvel, Dieter, Lavigne, Rob, Wattiau, Pierre, Mast, Jan, Ragimbeau, Catherine, Mossong, Joel, Scheres, Jacques, Chanishvili, Nina, Vaneechoutte, Mario, Pirnay, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528706/
https://www.ncbi.nlm.nih.gov/pubmed/23285164
http://dx.doi.org/10.1371/journal.pone.0052709