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Anti-Amyloid-β-Mediated Positron Emission Tomography Imaging in Alzheimer's Disease Mouse Brains

Antibody-mediated imaging of amyloid β (Aβ) in Alzheimer's disease (AD) offers a promising strategy to detect and monitor specific Aβ species, such as oligomers, that have important pathological and therapeutic relevance. The major current limitation of antibodies as a diagnostic and imaging de...

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Detalles Bibliográficos
Autores principales: McLean, Daniel, Cooke, Michael J., Wang, Yuanfei, Green, David, Fraser, Paul E., George-Hyslop, Peter St, Shoichet, Molly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528731/
https://www.ncbi.nlm.nih.gov/pubmed/23284831
http://dx.doi.org/10.1371/journal.pone.0051958