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Anti-Amyloid-β-Mediated Positron Emission Tomography Imaging in Alzheimer's Disease Mouse Brains
Antibody-mediated imaging of amyloid β (Aβ) in Alzheimer's disease (AD) offers a promising strategy to detect and monitor specific Aβ species, such as oligomers, that have important pathological and therapeutic relevance. The major current limitation of antibodies as a diagnostic and imaging de...
Autores principales: | McLean, Daniel, Cooke, Michael J., Wang, Yuanfei, Green, David, Fraser, Paul E., George-Hyslop, Peter St, Shoichet, Molly S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528731/ https://www.ncbi.nlm.nih.gov/pubmed/23284831 http://dx.doi.org/10.1371/journal.pone.0051958 |
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