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The N-Terminal HSDCIF Motif Is Required for Cell Surface Trafficking and Dimerization of Family B G Protein Coupled Receptor PAC1

PAC1 is PACAP (pituitary adenylate cyclase-activating polypeptide) preferring receptor belonging to class B G protein coupled receptor (GPCR) mediating the most effects of PACAP. The important role of G protein coupled receptor homo/heteromerization in receptor folding, maturation, trafficking, and...

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Detalles Bibliográficos
Autores principales: Yu, Rongjie, Guo, Xiaoling, Zhong, Jiaping, Li, Mei, Zeng, Zhixing, Zhang, Huahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528735/
https://www.ncbi.nlm.nih.gov/pubmed/23284775
http://dx.doi.org/10.1371/journal.pone.0051811