Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

OBJECTIVE: Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured epithelial cells (epithelial to mesenchymal transition, EMT) may serve as a source of fibrosis. The macrolide antibiotic azithromyci...

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Detalles Bibliográficos
Autores principales: Banerjee, Balarka, Musk, Michael, Sutanto, Erika N., Yerkovich, Stephanie T., Hopkins, Peter, Knight, Darryl A., Lindsey-Temple, Suzanna, Stick, Stephen M., Kicic, Anthony, Chambers, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528745/
https://www.ncbi.nlm.nih.gov/pubmed/23284981
http://dx.doi.org/10.1371/journal.pone.0052309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528745/
https://www.ncbi.nlm.nih.gov/pubmed/23284981
http://dx.doi.org/10.1371/journal.pone.0052309

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