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C. elegans Expressing Human β(2)-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

Availability of living organisms to mimic key step of amyloidogenesis of human protein has become an indispensable tool for our translation approach aiming at filling the deep gap existing between the biophysical and biochemical data obtained in vitro and the pathological features observed in patien...

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Detalles Bibliográficos
Autores principales: Diomede, Luisa, Soria, Cristina, Romeo, Margherita, Giorgetti, Sofia, Marchese, Loredana, Mangione, Patrizia Palma, Porcari, Riccardo, Zorzoli, Irene, Salmona, Mario, Bellotti, Vittorio, Stoppini, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528749/
https://www.ncbi.nlm.nih.gov/pubmed/23284985
http://dx.doi.org/10.1371/journal.pone.0052314