Unique In Vitro and In Vivo Thrombopoietic Activities of Ingenol 3,20 Dibenzoate, A Ca(++)-Independent Protein Kinase C Isoform Agonist

Thrombopoiesis following severe bone marrow injury frequently is delayed, thereby resulting in life-threatening thrombocytopenia for which there are limited treatment options. The reasons for these delays in recovery are not well understood. Protein kinase C (PKC) agonists promote megakaryocyte diff...

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Detalles Bibliográficos
Autores principales: Racke, Frederick K., Baird, Maureen, Barth, Rolf F., Huo, Tianyao, Yang, Weilian, Gupta, Nilendu, Weldon, Michael, Rutledge, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528756/
https://www.ncbi.nlm.nih.gov/pubmed/23284657
http://dx.doi.org/10.1371/journal.pone.0051059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528756/
https://www.ncbi.nlm.nih.gov/pubmed/23284657
http://dx.doi.org/10.1371/journal.pone.0051059

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