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Global Effect of Inauhzin on Human p53-Responsive Transcriptome

BACKGROUND: Previously, we reported that Inauhzin (INZ) induces p53 activity and suppresses tumor growth by inhibiting Sirt1. However, it remains unknown whether INZ may globally affect p53-dependent gene expression or not. Herein, we have conducted microarray and real-time PCR analyses of gene expr...

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Detalles Bibliográficos
Autores principales: Liao, Jun-Ming, Zeng, Shelya X., Zhou, Xiang, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528779/
https://www.ncbi.nlm.nih.gov/pubmed/23284922
http://dx.doi.org/10.1371/journal.pone.0052172