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Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole

Estrogen synthesis suppression induced by aromatase inhibitors in breast cancer (BC) patients may be affected by single nucleotide polymorphisms (SNPs) of the gene encoding aromatase enzyme, CYP19A1. We assessed the association between plasma estrone sulfate (ES), letrozole treatment, and four SNPs...

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Detalles Bibliográficos
Autores principales: Lunardi, G., Piccioli, P., Bruzzi, P., Notaro, R., Lastraioli, S., Serra, M., Marroni, P., Bighin, C., Mansutti, M., Puglisi, F., Porpiglia, M., Ponzone, R., Bisagni, G., Garrone, O., Cavazzini, G., Clavarezza, M., Del Mastro, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528956/
https://www.ncbi.nlm.nih.gov/pubmed/23129173
http://dx.doi.org/10.1007/s10549-012-2306-z