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A randomized, controlled non-inferiority trial comparing A(H1N1)pmd09 vaccine antigen, with and without AS03 adjuvant system, co-administered or sequentially administered with an inactivated trivalent seasonal influenza vaccine

BACKGROUND: At the time of the influenza A(H1N1)pmd09 pandemic it was not known if concurrent or sequential administration of seasonal trivalent influenza vaccine (TIV) with pandemic vaccine was preferred. METHODS: Immunogenicity and safety were assessed in 871 healthy subjects aged 19–40 years who...

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Detalles Bibliográficos
Autores principales: Langley, Joanne M, Frenette, Louise, Chu, Laurence, McNeil, Shelly, Halperin, Scott, Li, Ping, Vaughn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529122/
https://www.ncbi.nlm.nih.gov/pubmed/23110320
http://dx.doi.org/10.1186/1471-2334-12-279