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Natural killer lytic-associated molecule plays a role in controlling tumor dissemination and metastasis

Natural killer lytic-associated molecule (NKLAM) is an E3 ubiquitin ligase that plays a major role in the cytolytic activity of NK cells. NKLAM is rapidly synthesized and then targeted to the granule membranes of NK cells upon NK activation. Previous studies have shown an essential role for NKLAM in...

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Detalles Bibliográficos
Autores principales: Hoover, Richard G., Gullickson, Gail, Kornbluth, Jacki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529306/
https://www.ncbi.nlm.nih.gov/pubmed/23269922
http://dx.doi.org/10.3389/fimmu.2012.00393