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Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models

Fanconi anaemia (FA) is a rare autosomal recessive or X-linked inherited disease characterised by an increased incidence of bone marrow failure (BMF), haematological malignancies and solid tumours. Cells from individuals with FA show a pronounced sensitivity to DNA interstrand crosslink (ICL)-induci...

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Detalles Bibliográficos
Autores principales: Bakker, Sietske T., de Winter, Johan P., te Riele, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529337/
https://www.ncbi.nlm.nih.gov/pubmed/23268537
http://dx.doi.org/10.1242/dmm.009795