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Levocetirizine Inhibits Migration of Immune Cells to Lymph Nodes and Induces Treg Cells in a Murine Type I Allergic Conjunctivitis Model

BACKGROUND & PURPOSE: Levocetirizine is a histamine H(1) receptor antagonist. Here, we utilised DO11.10TCR transgenic mice to establish an antigen-specific T cell-dependent allergic conjunctivitis (AC) model to determine the effect of the topical application of an ophthalmic formulation of Levoc...

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Detalles Bibliográficos
Autores principales: García-Zepeda, Sihomara, Estrada-Muñiz, Elizabet, Elizondo, Guillermo, Terrazas, Luis I, Rodríguez-Sosa, Miriam, Quintana-Hau, Juan D, Tornero-Montaño, Rubén, Baiza-Durán, Leopoldo, Vega, Libia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529389/
https://www.ncbi.nlm.nih.gov/pubmed/23284599
http://dx.doi.org/10.2174/1874364101206010129