Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo

The Aβ peptide aggregates into amyloid plaques at presymptomatic stages of Alzheimer's disease, but the temporal relationship between plaque formation and neuronal dysfunction is poorly understood. Here, we demonstrate that the connectivity of the peripheral olfactory neural circuit is perturbe...

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Detalles Bibliográficos
Autores principales: Cao, Luxiang, Schrank, Benjamin R., Rodriguez, Steve, Benz, Eric G., Moulia, Thomas W., Rickenbacher, Gregory T., Gomez, Alexis C., Levites, Yona, Edwards, Sarah R., Golde, Todd E., Hyman, Bradley T., Barnea, Gilad, Albers, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529477/
https://www.ncbi.nlm.nih.gov/pubmed/22910355
http://dx.doi.org/10.1038/ncomms2013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529477/
https://www.ncbi.nlm.nih.gov/pubmed/22910355
http://dx.doi.org/10.1038/ncomms2013

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