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Aβ alters the connectivity of olfactory neurons in the absence of amyloid plaques in vivo
The Aβ peptide aggregates into amyloid plaques at presymptomatic stages of Alzheimer's disease, but the temporal relationship between plaque formation and neuronal dysfunction is poorly understood. Here, we demonstrate that the connectivity of the peripheral olfactory neural circuit is perturbe...
Autores principales: | Cao, Luxiang, Schrank, Benjamin R., Rodriguez, Steve, Benz, Eric G., Moulia, Thomas W., Rickenbacher, Gregory T., Gomez, Alexis C., Levites, Yona, Edwards, Sarah R., Golde, Todd E., Hyman, Bradley T., Barnea, Gilad, Albers, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529477/ https://www.ncbi.nlm.nih.gov/pubmed/22910355 http://dx.doi.org/10.1038/ncomms2013 |
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