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Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings
BACKGROUND: Considering the observations that linoleic acid conjugated with paclitaxel (CLA-PTX) possesses antitumor activity against brain tumors, is able to cross the blood–brain barrier, but has poor water solubility, the purpose of this study was to prepare a novel CLA-PTX microemulsion and eval...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529648/ https://www.ncbi.nlm.nih.gov/pubmed/23269869 http://dx.doi.org/10.2147/IJN.S38927 |