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Simultaneous learning of instantaneous and time-delayed genetic interactions using novel information theoretic scoring technique

BACKGROUND: Understanding gene interactions is a fundamental question in systems biology. Currently, modeling of gene regulations using the Bayesian Network (BN) formalism assumes that genes interact either instantaneously or with a certain amount of time delay. However in reality, biological regula...

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Detalles Bibliográficos
Autores principales: Morshed, Nizamul, Chetty, Madhu, Xuan Vinh, Nguyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529704/
https://www.ncbi.nlm.nih.gov/pubmed/22691450
http://dx.doi.org/10.1186/1752-0509-6-62