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Structure and Dynamics of the M(3) Muscarinic Acetylcholine Receptor

Acetylcholine (ACh), the first neurotransmitter to be identified(1), exerts many of its physiological actions via activation of a family of G protein-coupled receptors (GPCRs) known as muscarinic ACh receptors (mAChRs). Although the five mAChR subtypes (M(1)-M(5)) share a high degree of sequence hom...

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Detalles Bibliográficos
Autores principales: Kruse, Andrew C., Hu, Jianxin, Pan, Albert C., Arlow, Daniel H., Rosenbaum, Daniel M., Rosemond, Erica, Green, Hillary F., Liu, Tong, Chae, Pil Seok, Dror, Ron O., Shaw, David E., Weis, William I., Wess, Jurgen, Kobilka, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529910/
https://www.ncbi.nlm.nih.gov/pubmed/22358844
http://dx.doi.org/10.1038/nature10867