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Sibship T(2 )association tests of complex diseases for tightly linked markers

For population case-control association studies, the false-positive rates can be high due to inappropriate controls, which can occur if there is population admixture or stratification. Moreover, it is not always clear how to choose appropriate controls. Alternatively, the parents or normal sibs can...

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Detalles Bibliográficos
Autores principales: Fan, Ruzong, Knapp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530186/
https://www.ncbi.nlm.nih.gov/pubmed/16004725
http://dx.doi.org/10.1186/1479-7364-2-2-90