Atomic Scissors: A New Method of Tracking the 5-Bromo-2′-Deoxyuridine-Labeled DNA In Situ

A new method of the light microscopy detection of BrdU-labeled DNA in situ is described. It is based on the oxidative attack at the deoxyribose moiety by copper(I) in the presence of oxygen, which leads to the abstraction of hydrogen atom from deoxyribose culminating in the elimination of the nucleo...

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Detalles Bibliográficos
Autores principales: Ligasová, Anna, Strunin, Dmytro, Liboska, Radek, Rosenberg, Ivan, Koberna, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530445/
https://www.ncbi.nlm.nih.gov/pubmed/23300711
http://dx.doi.org/10.1371/journal.pone.0052584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530445/
https://www.ncbi.nlm.nih.gov/pubmed/23300711
http://dx.doi.org/10.1371/journal.pone.0052584

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