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Nano-Scale Alignment of Proteins on a Flexible DNA Backbone

Nano-scale alignment of several proteins with freedom of motion is equivalent to an enormous increase in effective local concentration of proteins and will enable otherwise impossible weak and/or cooperative associations between them or with their ligands. For this purpose, a DNA backbone made of si...

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Detalles Bibliográficos
Autores principales: Nojima, Tatsuya, Konno, Hiroki, Kodera, Noriyuki, Seio, Kohji, Taguchi, Hideki, Yoshida, Masasuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530504/
https://www.ncbi.nlm.nih.gov/pubmed/23300700
http://dx.doi.org/10.1371/journal.pone.0052534