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Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates

The identification of protein kinase targets remains a significant bottleneck for our understanding of signal transduction in normal and diseased cellular states. Kinases recognize their substrates in part through sequence motifs on substrate proteins, which, to date, have most effectively been eluc...

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Detalles Bibliográficos
Autores principales: Chou, Michael F., Prisic, Sladjana, Lubner, Joshua M., Church, George M., Husson, Robert N., Schwartz, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530509/
https://www.ncbi.nlm.nih.gov/pubmed/23300758
http://dx.doi.org/10.1371/journal.pone.0052747