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Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates
The identification of protein kinase targets remains a significant bottleneck for our understanding of signal transduction in normal and diseased cellular states. Kinases recognize their substrates in part through sequence motifs on substrate proteins, which, to date, have most effectively been eluc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530509/ https://www.ncbi.nlm.nih.gov/pubmed/23300758 http://dx.doi.org/10.1371/journal.pone.0052747 |