HSP70 Enhances Immunosuppressive Function of CD4(+)CD25(+)FoxP3(+) T Regulatory Cells and Cytotoxicity in CD4(+)CD25(−) T Cells

Human CD4(+)CD25(+)FoxP3(+) T regulatory cells (Tregs) control effector T cells and play a central role in peripheral tolerance and immune homeostasis. Heat shock protein 70 (HSP70) is a major immunomodulatory molecule, but its effect on the functions of Tregs is not well understood. To investigate...

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Detalles Bibliográficos
Autores principales: Wachstein, Julian, Tischer, Sabine, Figueiredo, Constanca, Limbourg, Anne, Falk, Christine, Immenschuh, Stephan, Blasczyk, Rainer, Eiz-Vesper, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530531/
https://www.ncbi.nlm.nih.gov/pubmed/23300563
http://dx.doi.org/10.1371/journal.pone.0051747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530531/
https://www.ncbi.nlm.nih.gov/pubmed/23300563
http://dx.doi.org/10.1371/journal.pone.0051747

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