Local Administration of Soluble CD40:Fc to the Salivary Glands of Non-Obese Diabetic Mice Does Not Ameliorate Autoimmune Inflammation

OBJECTIVE: CD40–CD154 (CD40 ligand) interaction in the co-stimulatory pathway is involved in many (auto)immune processes and both molecules are upregulated in salivary glands of Sjögren’s syndrome (SS) patients. Interference within the CD40 pathway has ameliorated (auto)inflammation in a number of d...

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Detalles Bibliográficos
Autores principales: Roescher, Nienke, Vosters, Jelle L., Lai, Zhenan, Uede, Toshimitsu, Tak, Paul P., Chiorini, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530540/
https://www.ncbi.nlm.nih.gov/pubmed/23300544
http://dx.doi.org/10.1371/journal.pone.0051375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530540/
https://www.ncbi.nlm.nih.gov/pubmed/23300544
http://dx.doi.org/10.1371/journal.pone.0051375

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