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A Comprehensive Evaluation of Alignment Algorithms in the Context of RNA-Seq
Transcriptome sequencing (RNA-Seq) overcomes limitations of previously used RNA quantification methods and provides one experimental framework for both high-throughput characterization and quantification of transcripts at the nucleotide level. The first step and a major challenge in the analysis of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530550/ https://www.ncbi.nlm.nih.gov/pubmed/23300661 http://dx.doi.org/10.1371/journal.pone.0052403 |