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A Comprehensive Evaluation of Alignment Algorithms in the Context of RNA-Seq

Transcriptome sequencing (RNA-Seq) overcomes limitations of previously used RNA quantification methods and provides one experimental framework for both high-throughput characterization and quantification of transcripts at the nucleotide level. The first step and a major challenge in the analysis of...

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Detalles Bibliográficos
Autores principales: Lindner, Robert, Friedel, Caroline C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530550/
https://www.ncbi.nlm.nih.gov/pubmed/23300661
http://dx.doi.org/10.1371/journal.pone.0052403