Naringenin Decreases Invasiveness and Metastasis by Inhibiting TGF-β-Induced Epithelial to Mesenchymal Transition in Pancreatic Cancer Cells

Epithelial to mesenchymal transition (EMT) promotes cellular motility, invasiveness and metastasis during embryonic development and tumorigenesis. Transforming growth factor-β (TGF-β) signaling pathway is a key regulator of EMT. A lot of evidences suggest that this process is Smad3-dependent. Herein...

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Detalles Bibliográficos
Autores principales: Lou, Changjie, Zhang, Fayun, Yang, Ming, Zhao, Juan, Zeng, Wenfeng, Fang, Xiaocui, Zhang, Yanqiao, Zhang, Chunling, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530567/
https://www.ncbi.nlm.nih.gov/pubmed/23300530
http://dx.doi.org/10.1371/journal.pone.0050956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530567/
https://www.ncbi.nlm.nih.gov/pubmed/23300530
http://dx.doi.org/10.1371/journal.pone.0050956

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