Dopamine Transporter Loss in 6-OHDA Parkinson’s Model Is Unmet by Parallel Reduction in Dopamine Uptake

The dopamine transporter (DAT) regulates synaptic dopamine (DA) in striatum and modulation of DAT can affect locomotor activity. Thus, in Parkinson’s disease (PD), DAT loss could affect DA clearance and locomotor activity. The locomotor benefits of L-DOPA may be mediated by transport through monoami...

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Detalles Bibliográficos
Autores principales: Chotibut, Tanya, Apple, Deana M., Jefferis, Rebecca, Salvatore, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530604/
https://www.ncbi.nlm.nih.gov/pubmed/23300642
http://dx.doi.org/10.1371/journal.pone.0052322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530604/
https://www.ncbi.nlm.nih.gov/pubmed/23300642
http://dx.doi.org/10.1371/journal.pone.0052322

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