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Inhibition of the Pim1 Oncogene Results in Diminished Visual Function

Our objective was to profile genetic pathways whose differential expression correlates with maturation of visual function in zebrafish. Bioinformatic analysis of transcriptomic data revealed Jak-Stat signalling as the pathway most enriched in the eye, as visual function develops. Real-time PCR, west...

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Detalles Bibliográficos
Autores principales: Yin, Jun, Shine, Lisa, Raycroft, Francis, Deeti, Sudhakar, Reynolds, Alison, Ackerman, Kristin M., Glaviano, Antonino, O'Farrell, Sean, O'Leary, Olivia, Kilty, Claire, Kennedy, Ciaran, McLoughlin, Sarah, Rice, Megan, Russell, Eileen, Higgins, Desmond G., Hyde, David R., Kennedy, Breandan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530609/
https://www.ncbi.nlm.nih.gov/pubmed/23300608
http://dx.doi.org/10.1371/journal.pone.0052177