CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling

CIB1 is a 22-kDa regulatory protein previously implicated in cell survival and proliferation. However, the mechanism by which CIB1 regulates these processes is poorly defined. Here we report that CIB1 depletion in SK-N-SH neuroblastoma and MDA-MB-468 breast cancer cells promotes non-apoptotic, caspa...

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Detalles Bibliográficos
Autores principales: Leisner, Tina M., Moran, Cassandra, Holly, Stephen P., Parise, Leslie V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530648/
https://www.ncbi.nlm.nih.gov/pubmed/22964641
http://dx.doi.org/10.1038/onc.2012.408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530648/
https://www.ncbi.nlm.nih.gov/pubmed/22964641
http://dx.doi.org/10.1038/onc.2012.408

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