GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility

Estrogen receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcription events that promote tumor growth. Differences in enhancer occupancy by ESR1 contribute to the diverse expression profiles and clinical outcome observed in breas...

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Detalles Bibliográficos
Autores principales: Theodorou, Vasiliki, Stark, Rory, Menon, Suraj, Carroll, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530671/
https://www.ncbi.nlm.nih.gov/pubmed/23172872
http://dx.doi.org/10.1101/gr.139469.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530671/
https://www.ncbi.nlm.nih.gov/pubmed/23172872
http://dx.doi.org/10.1101/gr.139469.112

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