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Modeling kinetic rate variation in third generation DNA sequencing data to detect putative modifications to DNA bases

Current generation DNA sequencing instruments are moving closer to seamlessly sequencing genomes of entire populations as a routine part of scientific investigation. However, while significant inroads have been made identifying small nucleotide variation and structural variations in DNA that impact...

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Detalles Bibliográficos
Autores principales: Schadt, Eric E., Banerjee, Onureena, Fang, Gang, Feng, Zhixing, Wong, Wing H., Zhang, Xuegong, Kislyuk, Andrey, Clark, Tyson A., Luong, Khai, Keren-Paz, Alona, Chess, Andrew, Kumar, Vipin, Chen-Plotkin, Alice, Sondheimer, Neal, Korlach, Jonas, Kasarskis, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530673/
https://www.ncbi.nlm.nih.gov/pubmed/23093720
http://dx.doi.org/10.1101/gr.136739.111