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Haplotype-based profiling of subtle allelic imbalance with SNP arrays

Due to limitations of surgical dissection and tumor heterogeneity, tumor samples collected for cancer genomics studies are often heavily diluted with normal tissue or contain subpopulations of cells harboring important aberrations. Methods for profiling tumor-associated allelic imbalance in such sce...

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Detalles Bibliográficos
Autores principales: Vattathil, Selina, Scheet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530675/
https://www.ncbi.nlm.nih.gov/pubmed/23028187
http://dx.doi.org/10.1101/gr.141374.112