Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient

Cases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthrac...

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Autores principales: Genet, Philippe, Chaoui, Driss, Masse, Virginie, Al Jijakli, Ahmad, Arakelyan, Nina, Sutton, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530765/
https://www.ncbi.nlm.nih.gov/pubmed/23304578
http://dx.doi.org/10.1155/2012/180204
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author Genet, Philippe
Chaoui, Driss
Masse, Virginie
Al Jijakli, Ahmad
Arakelyan, Nina
Sutton, Laurent
author_facet Genet, Philippe
Chaoui, Driss
Masse, Virginie
Al Jijakli, Ahmad
Arakelyan, Nina
Sutton, Laurent
author_sort Genet, Philippe
collection PubMed
description Cases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthracyclin-based chemotherapy was unsuccessful. The literature review was performed focusing on incidence, clinical characteristics, prognosis, and physiopathology of ALCL in HIV patients. More data are needed to improve the knowledge of such cases and to define a better treatment approach.
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spelling pubmed-35307652013-01-09 Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient Genet, Philippe Chaoui, Driss Masse, Virginie Al Jijakli, Ahmad Arakelyan, Nina Sutton, Laurent Case Rep Hematol Case Report Cases of anaplastic large-cell lymphoma (ALCL) of T phenotype are sparse in the setting of HIV patients. We report herein a case of T-ALCL, with an advanced stage, pulmonary involvement, high HIV viral load, and low CD4 level. Anaplastic lymphoma kinase (ALK) protein expression was negative. Anthracyclin-based chemotherapy was unsuccessful. The literature review was performed focusing on incidence, clinical characteristics, prognosis, and physiopathology of ALCL in HIV patients. More data are needed to improve the knowledge of such cases and to define a better treatment approach. Hindawi Publishing Corporation 2012 2012-12-12 /pmc/articles/PMC3530765/ /pubmed/23304578 http://dx.doi.org/10.1155/2012/180204 Text en Copyright © 2012 Philippe Genet et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Genet, Philippe
Chaoui, Driss
Masse, Virginie
Al Jijakli, Ahmad
Arakelyan, Nina
Sutton, Laurent
Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title_full Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title_fullStr Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title_full_unstemmed Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title_short Anaplastic Large Cell Lymphoma Occurring in an HIV-Positive Patient
title_sort anaplastic large cell lymphoma occurring in an hiv-positive patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530765/
https://www.ncbi.nlm.nih.gov/pubmed/23304578
http://dx.doi.org/10.1155/2012/180204
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