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Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells

Ire1 is an endoplasmic reticulum (ER) transmembrane protein that senses disturbances in protein folding homeostasis and contributes to a multifaceted response to stress. The nuclease activity of Ire1, in addition to splicing the mRNA encoding the transcription factor Xbp1, mediates mRNA degradation...

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Detalles Bibliográficos
Autores principales: Gaddam, Deepika, Stevens, Nicole, Hollien, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530775/
https://www.ncbi.nlm.nih.gov/pubmed/23135994
http://dx.doi.org/10.1091/mbc.E12-06-0491