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Endoplasmic spreading requires coalescence of vimentin intermediate filaments at force-bearing adhesions

For cells to develop long-range forces and carry materials to the periphery, the microtubule and organelle-rich region at the center of the cell—the endoplasm—needs to extend to near the cell edge. Depletion of the actin cross-linking protein filamin A (FlnA) causes a collapse of the endoplasm into...

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Detalles Bibliográficos
Autores principales: Lynch, Christopher D., Lazar, Andre M., Iskratsch, Thomas, Zhang, Xian, Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530776/
https://www.ncbi.nlm.nih.gov/pubmed/23115305
http://dx.doi.org/10.1091/mbc.E12-05-0377