Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin

Actin filament severing is critical for the dynamic turnover of cellular actin networks. Cofilin severs filaments, but additional factors may be required to increase severing efficiency in vivo. Srv2/cyclase-associated protein (CAP) is a widely expressed protein with a role in binding and recycling...

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Detalles Bibliográficos
Autores principales: Chaudhry, Faisal, Breitsprecher, Dennis, Little, Kristin, Sharov, Grigory, Sokolova, Olga, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530777/
https://www.ncbi.nlm.nih.gov/pubmed/23135996
http://dx.doi.org/10.1091/mbc.E12-08-0589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530777/
https://www.ncbi.nlm.nih.gov/pubmed/23135996
http://dx.doi.org/10.1091/mbc.E12-08-0589

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