Molecular modeling, docking and ADMET studies towards development of novel Disopyramide analogs for potential inhibition of human voltage gated sodium channel proteins

The sodium “channelopathies” are the first among the ion channel diseases identified and have attracted widespread clinical and scientific interests. Human voltage gated sodium channels are sites of action of several antiarrhythmic drugs, local anesthetics and related antiepileptic drugs. The presen...

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Detalles Bibliográficos
Autores principales: Meraj, Khunza, Mahto, Manoj Kumar, Christina, N Blessy, Desai, Nidhi, Shahbazi, Sajad, Bhaskar, Matcha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530882/
https://www.ncbi.nlm.nih.gov/pubmed/23275710
http://dx.doi.org/10.6026/97320630081139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530882/
https://www.ncbi.nlm.nih.gov/pubmed/23275710
http://dx.doi.org/10.6026/97320630081139

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